Hebei Tianao Technology Co.,Ltd

1. It is prepared by methylation and esterification of dimethyl sulfate by gallic acid (or tannin acid), and then hydrazine hydrate reaction is carried out by hydrazine hydrate, and then oxidized by red blood salt. The yield of industrial production is more than 70%. 2. It is obtained from vanillaldehyde by bromination, hydrolysis and methylation. 3. P-nitrotoluene is used as raw material, redox, and then sodium nitrite diazotization and hydrolysis are used to obtain p-hydroxybenzaldehyde, which is obtained by bromination, dimethoxylatation and methylation. In addition, 3,4,5-trimethoxybenzaldehyde can also be prepared from trimethoxybenzonitrile and p-hydroxybenzaldehyde.
Properties: White to yellowish needle-like crystals.
Uses: For the synthesis of antibacterial synergistic drug trimethoprim; It is used as an important intermediate of sulfonamide synergist and antibacterial synergist TMP.