Creative Proteomics

A xenobiotic is a foreign chemical substance found within an organism that is not normally naturally produced by or expected to be present within that organism.<br />
The organism removes xenobiotics by xenobiotic metabolism, consisting of deactivation/activation and excretion of xenobiotics, which happen mostly in the liver. Hepatic enzymes are responsible for the metabolism of xenobiotics by first deactivating/activating them (oxidation, reduction, hydrolysis and/or hydration of the xenobiotic), and then conjugating thesecondary metabolites with glucuronic acid, sulphuric acid, or glutathione, followed by excretion in bile or urine.